Head & Neck · Reconstruction · Surgical case report with operative images

Giant Pilomatricoma of the Neck Misdiagnosed as Tubercular Lymphadenitis: Wide Local Excision and Two-Stage Deltopectoral Flap Reconstruction

Pilomatricoma presenting as a non-healing neck mass. Intended audience: ENT, head and neck, plastic and general surgeons.

Santosh Advance ENT Healthcare, HisarPublished 08 November 2026
De-identifiedPatient consent obtainedReferencedFor surgical education
Pilomatricoma presenting as a non-healing neck mass
Diagnosis
Pilomatricoma of the neck (misdiagnosed as TB)
Procedure
Wide local excision with skin
Defect
About 8 × 7.5 cm
Reconstruction
Deltopectoral flap, divided at day 21
Video
2 min · step-by-step

Operative video with step captions and geometric orientation markings. Summary video.

Abstract

Pilomatricoma is a benign adnexal tumour of hair-matrix origin, most often in the head and neck, and frequently misdiagnosed clinically. We describe a young adult treated empirically for tubercular lymphadenitis for six months, in whom a 7 × 6.5 cm right neck mass with a discharging sinus proved on biopsy to be pilomatricoma. Wide local excision with the involved skin left an 8 × 7.5 cm defect, reconstructed with a medially based deltopectoral flap and divided at three weeks.

Keywords: pilomatricoma; pilomatrixoma; neck mass; tubercular lymphadenitis; deltopectoral flap

Introduction

Pilomatricoma (calcifying epithelioma of Malherbe) usually presents as a firm, slow-growing subcutaneous nodule and is easily confused with other skin and neck masses [1]. In regions where tuberculosis is endemic, a non-healing neck mass may be treated empirically without tissue diagnosis.

Case presentation

A 21-year-old man had a right neck swelling for six months, treated as tubercular granuloma without response. The mass enlarged progressively with skin breakdown and a discharging sinus. Biopsy showed pilomatricoma.

Written informed consent for surgery and for de-identified educational use of images was obtained.

Geometric orientation, right lateral view: neck mass and the deltopectoral flap.
Geometric orientation, right lateral view: neck mass and the deltopectoral flap.
Right neck mass, 7 × 6.5 cm, with a discharging sinus.
Right neck mass, 7 × 6.5 cm, with a discharging sinus.

Surgical technique

  1. Marking with a safe margin

    Elliptical skin excision around the sinus and involved skin.

    Marking with a safe margin
    Marking with a safe margin
  2. Wide local excision

    Mass removed en bloc with the overlying skin.

    Wide local excision
    Wide local excision
  3. Defect and specimen

    Defect about 8 × 7.5 cm, too large for primary closure.

    Defect and specimen
    Defect and specimen
  4. Deltopectoral flap

    Medially based on internal mammary perforators, raised in the subfascial plane from lateral to medial and transposed to the neck; donor site closed primarily [2].

    Deltopectoral flap
    Deltopectoral flap
  5. Flap inset

    Defect covered.

    Flap inset
    Flap inset
  6. Second stage

    Flap division at day 21 after neovascularisation from the recipient bed; the unused pedicle returned to the chest.

    Second stage
    Second stage
  7. Final result

    Stable cover with acceptable contour.

    Final result
    Final result

Postoperative management

  • Wound care and flap monitoring; second-stage division at three weeks.
  • Histopathology of the excised specimen confirmed the diagnosis.

Discussion

A neck mass that does not respond to antitubercular treatment needs a tissue diagnosis before therapy is prolonged. Complete excision is curative for pilomatricoma, with a low recurrence rate. When excision leaves a large neck skin defect, the deltopectoral flap provides thin, reliable cover.

Learning points

  • Not every neck lump is TB: obtain a tissue diagnosis when there is no response to treatment.
  • Excise completely with the involved skin and sinus.
  • The deltopectoral flap is a reliable two-stage option for large neck skin defects.

References

  1. Hu JL, Yoo H, Kwon ST, et al. Clinical analysis and review of literature on pilomatrixoma in pediatric patients. Arch Craniofac Surg. 2020;21(5):288-293. https://doi.org/10.7181/acfs.2020.00528
  2. Bakamjian VY. A two-stage method for pharyngoesophageal reconstruction with a primary pectoral skin flap. Plast Reconstr Surg. 1965;36:173-184.

Written informed consent was obtained for surgery and for de-identified use of clinical images and video for education. No identifying information is shown; eyes are blurred where visible. This report is for medical education and does not replace individual clinical advice.

Surgical team

Dr Bhushan Kathuria & Team, Santosh Advance ENT Healthcare, Hisar. Consultants: Dr Bhushan Kathuria, Dr Parmod Jangra, Dr Harshvardhan. Clinical fellows: Dr Ayush, Dr Iqrorjon. Team · Fellowship and previous fellows.

How to cite

Kathuria B, and Team. Giant Pilomatricoma of the Neck Misdiagnosed as Tubercular Lymphadenitis: Wide Local Excision and Two-Stage Deltopectoral Flap Reconstruction. Surgical Perspective · Surgical Case Reports. 2026. Available at: https://bhushankathuria.com/case-pilomatricoma-neck-deltopectoral-flap.html

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