2 min 24 s · patient consent taken · patient identity not shown · for surgical education
Advanced hypopharyngeal cancer: laryngopharyngectomy with a tubed pectoralis major flap
Squamous cell carcinoma of the hypopharynx (pyriform sinus, posterior pharyngeal wall and postcricoid region, extending to the glottis) in a man in his sixties, first tracheostomised for stridor. CT showed bilateral nodal disease, with the right nodal mass invading the external carotid artery; PET-CT showed disease confined to the neck. Upfront surgery was followed by chemoradiotherapy.
Staging (AJCC 8th)
- T: several subsites and the glottis, airway closed: at least T3; T4a if cartilage, thyroid gland or central soft tissue is invaded
- N: right nodal mass invading the external carotid artery = clinical extranodal extension, N3b
- M: PET-CT negative, M0
- cT3–4a cN3b cM0 = stage IVB; histopathology gives the final pT, pN, ENE and margins
Why upfront surgery
- Organ preservation suits a larynx worth keeping; this one had already closed the airway
- Salvage surgery after failed chemoradiotherapy carries more fistula and wound breakdown
- External carotid involvement is resectable; common or internal carotid encasement would not be
Operative steps
- Incisions marked around the tracheostome
- Right radical neck dissection; invaded external carotid artery ligated, common and internal carotid preserved
- Left modified radical neck dissection
- Total laryngectomy, total pharyngectomy and total thyroidectomy in one piece
- Circumferential defect from oropharynx to cervical oesophagus
- Pectoralis major myocutaneous flap raised, tunnelled and tubed
- Neck closed; permanent tracheostoma
References
- Lydiatt WM et al. CA Cancer J Clin 2017;67:122-37
- Lefebvre JL et al. J Natl Cancer Inst 1996;88:890-9
- Weber RS et al. Arch Otolaryngol Head Neck Surg 2003;129:44-9
- Bernier J et al. / Cooper JS et al. N Engl J Med 2004;350:1945-52 / 1937-44
